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Pooled Analysis of the Prognostic and Predictive Effects of KRAS Mutation Status and KRAS Mutation Subtype in Early-Stage Resected Non–Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy
PURPOSE: We undertook this analysis of KRAS mutation in four trials of adjuvant chemotherapy (ACT) versus observation (OBS) to clarify the prognostic/predictive roles of KRAS in non–small-cell lung cancer (NSCLC). METHODS: KRAS mutation was determined in blinded fashion. Exploratory analyses were pe...
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| 發表在: | J Clin Oncol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Clinical Oncology
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881333/ https://ncbi.nlm.nih.gov/pubmed/23630215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.48.1390 |
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