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Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV

BACKGROUND: Many HIV infected individuals with suppressed viral loads experience chronic immune activation frequently developing neurological impairment designated as HIV associated neurocognitive disorder (HAND). Adjunctive therapies may reduce HIV associated inflammation and therefore decrease the...

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書誌詳細
出版年:J Transl Med
主要な著者: Barrett, Jeffrey S., Spitsin, Sergei, Moorthy, Ganesh, Barrett, Kyle, Baker, Kate, Lackner, Andrew, Tulic, Florin, Winters, Angela, Evans, Dwight L., Douglas, Steven D.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880976/
https://ncbi.nlm.nih.gov/pubmed/27230663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0904-y
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