Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV

BACKGROUND: Many HIV infected individuals with suppressed viral loads experience chronic immune activation frequently developing neurological impairment designated as HIV associated neurocognitive disorder (HAND). Adjunctive therapies may reduce HIV associated inflammation and therefore decrease the...

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Vydáno v:J Transl Med
Hlavní autoři: Barrett, Jeffrey S., Spitsin, Sergei, Moorthy, Ganesh, Barrett, Kyle, Baker, Kate, Lackner, Andrew, Tulic, Florin, Winters, Angela, Evans, Dwight L., Douglas, Steven D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880976/
https://ncbi.nlm.nih.gov/pubmed/27230663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0904-y
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