Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV

BACKGROUND: Many HIV infected individuals with suppressed viral loads experience chronic immune activation frequently developing neurological impairment designated as HIV associated neurocognitive disorder (HAND). Adjunctive therapies may reduce HIV associated inflammation and therefore decrease the...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Barrett, Jeffrey S., Spitsin, Sergei, Moorthy, Ganesh, Barrett, Kyle, Baker, Kate, Lackner, Andrew, Tulic, Florin, Winters, Angela, Evans, Dwight L., Douglas, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880976/
https://ncbi.nlm.nih.gov/pubmed/27230663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0904-y
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