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The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach

DNA methylation and demethylation are opposing processes that when in balance create stable patterns of epigenetic memory. The control of DNA methylation pattern formation by replication dependent and independent demethylation processes has been suggested to be influenced by Tet mediated oxidation o...

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Publicat a:PLoS Comput Biol
Autors principals: Giehr, Pascal, Kyriakopoulos, Charalampos, Ficz, Gabriella, Wolf, Verena, Walter, Jörn
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880293/
https://ncbi.nlm.nih.gov/pubmed/27224554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004905
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