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The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach

DNA methylation and demethylation are opposing processes that when in balance create stable patterns of epigenetic memory. The control of DNA methylation pattern formation by replication dependent and independent demethylation processes has been suggested to be influenced by Tet mediated oxidation o...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Giehr, Pascal, Kyriakopoulos, Charalampos, Ficz, Gabriella, Wolf, Verena, Walter, Jörn
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880293/
https://ncbi.nlm.nih.gov/pubmed/27224554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004905
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