Sirtuin functions and modulation: from chemistry to the clinic

Sirtuins are NAD(+)-dependent histone deacetylases regulating important metabolic pathways in prokaryotes and eukaryotes and are involved in many biological processes such as cell survival, senescence, proliferation, apoptosis, DNA repair, cell metabolism, and caloric restriction. The seven members...

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Bibliografiska uppgifter
I publikationen:Clin Epigenetics
Huvudupphovsmän: Carafa, Vincenzo, Rotili, Dante, Forgione, Mariantonietta, Cuomo, Francesca, Serretiello, Enrica, Hailu, Gebremedhin Solomon, Jarho, Elina, Lahtela-Kakkonen, Maija, Mai, Antonello, Altucci, Lucia
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879741/
https://ncbi.nlm.nih.gov/pubmed/27226812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0224-3
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