Sirtuin functions and modulation: from chemistry to the clinic

Sirtuins are NAD(+)-dependent histone deacetylases regulating important metabolic pathways in prokaryotes and eukaryotes and are involved in many biological processes such as cell survival, senescence, proliferation, apoptosis, DNA repair, cell metabolism, and caloric restriction. The seven members...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Carafa, Vincenzo, Rotili, Dante, Forgione, Mariantonietta, Cuomo, Francesca, Serretiello, Enrica, Hailu, Gebremedhin Solomon, Jarho, Elina, Lahtela-Kakkonen, Maija, Mai, Antonello, Altucci, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879741/
https://ncbi.nlm.nih.gov/pubmed/27226812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0224-3
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