The Pan-Sirtuin Inhibitor MC2494 Regulates Mitochondrial Function in a Leukemia Cell Line

The involvement of sirtuins (SIRTs) in modulating metabolic and stress response pathways is attracting growing scientific interest. Some SIRT family members are located in mitochondria, dynamic organelles that perform several crucial functions essential for eukaryotic life. Mitochondrial dysfunction...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Carafa, Vincenzo, Russo, Rosita, Della Torre, Laura, Cuomo, Francesca, Dell'Aversana, Carmela, Sarno, Federica, Sgueglia, Giulia, Di Donato, Marzia, Rotili, Dante, Mai, Antonello, Nebbioso, Angela, Cobellis, Gilda, Chambery, Angela, Altucci, Lucia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255067/
https://ncbi.nlm.nih.gov/pubmed/32528892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00820
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