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Review: The HSP90 molecular chaperone—an enigmatic ATPase

The HSP90 molecular chaperone is involved in the activation and cellular stabilization of a range of ‘client’ proteins, of which oncogenic protein kinases and nuclear steroid hormone receptors are of particular biomedical significance. Work over the last two decades has revealed a conformational cyc...

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Détails bibliographiques
Publié dans:Biopolymers
Auteur principal: Pearl, Laurence H.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879513/
https://ncbi.nlm.nih.gov/pubmed/26991466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22835
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