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Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery
Hsp90 is a molecular chaperone essential for the activation and assembly of many key eukaryotic signalling and regulatory proteins. Hsp90 is assisted and regulated by co-chaperones that participate in an ordered series of dynamic multiprotein complexes, linked to Hsp90s conformationally coupled ATPa...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271799/ https://ncbi.nlm.nih.gov/pubmed/14739935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600060 |
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