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A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s

The conformationally coupled mechanism by which ATP is utilized by yeast Hsp90 is now well characterized. In contrast, ATP utilization by human Hsp90s is less well studied, and appears to operate differently. To resolve these conflicting models, we have conducted a side-by-side biochemical analysis...

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Hlavní autoři: Vaughan, Cara K, Piper, Peter W, Pearl, Laurence H, Prodromou, Chrisostomos
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702006/
https://ncbi.nlm.nih.gov/pubmed/19032597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06773.x
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