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High Intracellular Concentrations of Posaconazole Do Not Impact on Functional Capacities of Human Polymorphonuclear Neutrophils and Monocyte-Derived Macrophages In Vitro

Posaconazole is a commonly used antifungal for the prophylaxis and treatment of invasive fungal infections. We previously demonstrated that the intracellular concentration of posaconazole in peripheral blood mononuclear cells (PBMCs) and polymorphonuclear neutrophils (PMNs) was greatly increased com...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Farowski, Fedja, Cornely, Oliver A., Hartmann, Pia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879367/
https://ncbi.nlm.nih.gov/pubmed/27021317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02060-15
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