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High Intracellular Concentrations of Posaconazole Do Not Impact on Functional Capacities of Human Polymorphonuclear Neutrophils and Monocyte-Derived Macrophages In Vitro

Posaconazole is a commonly used antifungal for the prophylaxis and treatment of invasive fungal infections. We previously demonstrated that the intracellular concentration of posaconazole in peripheral blood mononuclear cells (PBMCs) and polymorphonuclear neutrophils (PMNs) was greatly increased com...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Farowski, Fedja, Cornely, Oliver A., Hartmann, Pia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879367/
https://ncbi.nlm.nih.gov/pubmed/27021317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02060-15
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