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High Intracellular Concentrations of Posaconazole Do Not Impact on Functional Capacities of Human Polymorphonuclear Neutrophils and Monocyte-Derived Macrophages In Vitro

Posaconazole is a commonly used antifungal for the prophylaxis and treatment of invasive fungal infections. We previously demonstrated that the intracellular concentration of posaconazole in peripheral blood mononuclear cells (PBMCs) and polymorphonuclear neutrophils (PMNs) was greatly increased com...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Farowski, Fedja, Cornely, Oliver A., Hartmann, Pia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879367/
https://ncbi.nlm.nih.gov/pubmed/27021317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02060-15
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