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High Intracellular Concentrations of Posaconazole Do Not Impact on Functional Capacities of Human Polymorphonuclear Neutrophils and Monocyte-Derived Macrophages In Vitro

Posaconazole is a commonly used antifungal for the prophylaxis and treatment of invasive fungal infections. We previously demonstrated that the intracellular concentration of posaconazole in peripheral blood mononuclear cells (PBMCs) and polymorphonuclear neutrophils (PMNs) was greatly increased com...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Farowski, Fedja, Cornely, Oliver A., Hartmann, Pia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879367/
https://ncbi.nlm.nih.gov/pubmed/27021317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02060-15
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