Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus

OBJECTIVE: Arterial stiffness increases with age, and is associated with adverse cardiovascular outcome including increased mortality. The effect of the oral small molecule SIRT1 activator, SRT2104, on arterial stiffness was examined in otherwise healthy cigarette smokers and participants with type...

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Veröffentlicht in:Open Heart
Hauptverfasser: Venkatasubramanian, Sowmya, Noh, Radzi M, Daga, Shruti, Langrish, Jeremy P, Mills, Nicholas L, Waterhouse, Brian R, Hoffmann, Ethan, Jacobson, Eric W, Lang, Ninian N, Frier, Brian M, Newby, David E
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2016
Schlagworte:
Aortic and Vascular Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879341/
https://ncbi.nlm.nih.gov/pubmed/27239324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/openhrt-2016-000402
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