Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus

OBJECTIVE: Arterial stiffness increases with age, and is associated with adverse cardiovascular outcome including increased mortality. The effect of the oral small molecule SIRT1 activator, SRT2104, on arterial stiffness was examined in otherwise healthy cigarette smokers and participants with type...

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Bibliographic Details
Published in:Open Heart
Main Authors: Venkatasubramanian, Sowmya, Noh, Radzi M, Daga, Shruti, Langrish, Jeremy P, Mills, Nicholas L, Waterhouse, Brian R, Hoffmann, Ethan, Jacobson, Eric W, Lang, Ninian N, Frier, Brian M, Newby, David E
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2016
Subjects:
Aortic and Vascular Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879341/
https://ncbi.nlm.nih.gov/pubmed/27239324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/openhrt-2016-000402
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