A Molecular Determinant of Subtype-Specific Desensitization in Ionotropic Glutamate Receptors

AMPA and NMDA receptors are glutamate-gated ion channels that mediate fast excitatory synaptic transmission throughout the nervous system. In the continual presence of glutamate, AMPA and NMDA receptors containing the GluN2A or GluN2B subunit enter into a nonconducting, desensitized state that can i...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Alsaloum, Matthew, Kazi, Rashek, Gan, Quan, Amin, Johansen, Wollmuth, Lonnie P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879209/
https://ncbi.nlm.nih.gov/pubmed/26937003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2667-15.2016
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