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Mechanism-Based Mathematical Model for Gating of Ionotropic Glutamate Receptors

We present a mathematical model for ionotropic glutamate receptors (iGluRs) that is built on mechanistic understanding and yields a number of thermodynamic and kinetic properties of channel gating. iGluRs are ligand-gated ion channels responsible for the vast majority of fast excitatory neurotransmi...

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Dades bibliogràfiques
Publicat a:J Phys Chem B
Autors principals: Dai, Jian, Wollmuth, Lonnie P., Zhou, Huan-Xiang
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552600/
https://ncbi.nlm.nih.gov/pubmed/25793415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b00521
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