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A Molecular Determinant of Subtype-Specific Desensitization in Ionotropic Glutamate Receptors

AMPA and NMDA receptors are glutamate-gated ion channels that mediate fast excitatory synaptic transmission throughout the nervous system. In the continual presence of glutamate, AMPA and NMDA receptors containing the GluN2A or GluN2B subunit enter into a nonconducting, desensitized state that can i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Alsaloum, Matthew, Kazi, Rashek, Gan, Quan, Amin, Johansen, Wollmuth, Lonnie P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879209/
https://ncbi.nlm.nih.gov/pubmed/26937003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2667-15.2016
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