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Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2

Glutamate receptors (GluRs) are the most abundant mediators of the fast excitatory neurotransmission in the human brain. Agonists will, after activation of the receptors, induce different degrees of desensitization. The efficacy of agonists strongly correlates with the agonist-induced closure of the...

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Detalhes bibliográficos
Main Authors: Holm, Mai Marie, Lunn, Marie-Louise, Traynelis, Stephen F., Kastrup, Jette S., Egebjerg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189343/
https://ncbi.nlm.nih.gov/pubmed/16099829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505522102
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