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Structure of an agonist-bound ionotropic glutamate receptor

Ionotropic glutamate receptors (iGluRs) mediate most excitatory neurotransmission in the central nervous system and function by opening their ion channel in response to binding of agonist glutamate. Here we report a structure of a homotetrameric rat GluA2 receptor in complex with partial agonist (S)...

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Publicat a:Science
Autors principals: Yelshanskaya, Maria V., Li, Minfen, Sobolevsky, Alexander I.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383034/
https://ncbi.nlm.nih.gov/pubmed/25103407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256508
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