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Structure of an agonist-bound ionotropic glutamate receptor
Ionotropic glutamate receptors (iGluRs) mediate most excitatory neurotransmission in the central nervous system and function by opening their ion channel in response to binding of agonist glutamate. Here we report a structure of a homotetrameric rat GluA2 receptor in complex with partial agonist (S)...
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| Publicado en: | Science |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4383034/ https://ncbi.nlm.nih.gov/pubmed/25103407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256508 |
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