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Translesion synthesis past guanine(C8)-thymine(N3) intrastrand cross-links catalyzed by selected A- and Y-family polymerases
Oxidatively generated guanine radicals in DNA can undergo various nucleophilic reactions including the formation of C8-guanine cross-links with adjacent or nearby N3-thymines in DNA in the presence of O(2). These G[8-3]T lesions have been identified in the DNA of human cells exposed to oxidative str...
Guardat en:
| Publicat a: | Mol Biosyst |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879090/ https://ncbi.nlm.nih.gov/pubmed/27102383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mb00160b |
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