Cargando...
Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage
Flt1 is a cell surface VEGF receptor which is cleaved to release an N-terminal ectodomain which binds VEGF and PlGF and can antagonize the effects of VEGF in the extracellular milieu. To further evaluate Flt1 processing we expressed tagged Flt1 constructs in HEK293 and COS7 cells where we demonstrat...
Guardado en:
| Publicado en: | Exp Cell Res |
|---|---|
| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879079/ https://ncbi.nlm.nih.gov/pubmed/27017929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.03.020 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|