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Down-regulation of hTERT and Cyclin D1 Transcription via PI3K/Akt and TGF-β Pathways in MCF-7 Cancer Cells with PX-866 and Raloxifene

Human telomerase reverse transcriptase (hTERT) is the catalytic and limiting component of telomerase and also a transcription factor. It is critical to the integrity of the ends of linear chromosomes and to the regulation, extent and rate of cell cycle progression in multicellular eukaryotes. The le...

詳細記述

保存先:
書誌詳細
出版年:Exp Cell Res
主要な著者: Peek, Gregory W., Tollefsbol, Trygve O.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879042/
https://ncbi.nlm.nih.gov/pubmed/27017931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.03.022
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