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Mechanisms for inhibition of colon cancer cells by sulforaphane through epigenetic modulation and hTERT down-regulation

Epigenetic modulations such as DNA methylation and histone modifications are becoming increasingly important for their ability to upregulate, down-regulate or silence genes without altering the DNA sequence. Many bioactive compounds have been shown to modify genetic and epigenetic profiles in variou...

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書目詳細資料
發表在:Curr Cancer Drug Targets
Main Authors: Martin, Samantha L., Kala, Rishabh, Tollefsbol, Trygve O.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577390/
https://ncbi.nlm.nih.gov/pubmed/28176652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1568009617666170206104032
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