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Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells

As a potential means to reduce proliferation of breast cancer cells, a multiple-pathway approach with no effect on control cells was explored. The human interactome being constructed by the Center for Cancer Systems Biology will prove indispensable to understanding composite effects of multiple path...

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Détails bibliographiques
Publié dans:J Cell Biochem
Auteurs principaux: Peek, Gregory W., Tollefsbol, Trygve O.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135016/
https://ncbi.nlm.nih.gov/pubmed/26660119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25462
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