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Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells

As a potential means to reduce proliferation of breast cancer cells, a multiple-pathway approach with no effect on control cells was explored. The human interactome being constructed by the Center for Cancer Systems Biology will prove indispensable to understanding composite effects of multiple path...

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Bibliographic Details
Published in:J Cell Biochem
Main Authors: Peek, Gregory W., Tollefsbol, Trygve O.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135016/
https://ncbi.nlm.nih.gov/pubmed/26660119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25462
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