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A mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorder
In 1994 in the Journal of Cell Science, Hennekes and Nigg reported that changing valine to arginine at the endoproteolytic cleavage site in chicken prelamin A abolishes its conversion to lamin A. The consequences of this mutation in an organism have remained unknown. We now report that the correspon...
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| 發表在: | J Cell Sci |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Company of Biologists Ltd
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878994/ https://ncbi.nlm.nih.gov/pubmed/27034136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.187302 |
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