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The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis
There is an urgent requirement for safe, oral and cost-effective drugs for the treatment of visceral leishmaniasis (VL). We report that delamanid (OPC-67683), an approved drug for multi-drug resistant tuberculosis, is a potent inhibitor of Leishmania donovani both in vitro and in vivo. Twice-daily o...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878867/ https://ncbi.nlm.nih.gov/pubmed/27215734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09744 |
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