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The ability of inner cell mass cells to self-renew as embryonic stem cells is acquired upon epiblast specification
The precise relationship of embryonic stem cells (ESC) to cells in the mouse embryo remains controversial. We present transcriptional and functional data to identify the embryonic counterpart of ESC. Marker profiling shows that ESC are distinct from early inner cell mass (ICM) and closely resemble p...
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| Veröffentlicht in: | Nat Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878656/ https://ncbi.nlm.nih.gov/pubmed/24859004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2965 |
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