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The ability of inner cell mass cells to self-renew as embryonic stem cells is acquired upon epiblast specification

The precise relationship of embryonic stem cells (ESC) to cells in the mouse embryo remains controversial. We present transcriptional and functional data to identify the embryonic counterpart of ESC. Marker profiling shows that ESC are distinct from early inner cell mass (ICM) and closely resemble p...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Cell Biol
Päätekijät: Boroviak, Thorsten, Loos, Remco, Bertone, Paul, Smith, Austin, Nichols, Jennifer
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878656/
https://ncbi.nlm.nih.gov/pubmed/24859004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2965
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