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The ability of inner cell mass cells to self-renew as embryonic stem cells is acquired upon epiblast specification

The precise relationship of embryonic stem cells (ESC) to cells in the mouse embryo remains controversial. We present transcriptional and functional data to identify the embryonic counterpart of ESC. Marker profiling shows that ESC are distinct from early inner cell mass (ICM) and closely resemble p...

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Bibliografiske detaljer
Udgivet i:Nat Cell Biol
Main Authors: Boroviak, Thorsten, Loos, Remco, Bertone, Paul, Smith, Austin, Nichols, Jennifer
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878656/
https://ncbi.nlm.nih.gov/pubmed/24859004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2965
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