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Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast

Single-cell profiling techniques create opportunities to delineate cell fate progression in mammalian development. Recent studies have provided transcriptome data from human pre-implantation embryos, in total comprising nearly 2000 individual cells. Interpretation of these data is confounded by biol...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Stirparo, Giuliano G., Boroviak, Thorsten, Guo, Ge, Nichols, Jennifer, Smith, Austin, Bertone, Paul
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818005/
https://ncbi.nlm.nih.gov/pubmed/29361568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.158501
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