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Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum

BACKGROUND: The yeast Saccharomyces cerevisiae provides intriguing possibilities for synthetic biology and bioprocess applications, but its use is still constrained by cellular characteristics that limit the product yields. Considering the production of advanced biopharmaceuticals, a major hindrance...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: de Ruijter, Jorg C., Koskela, Essi V., Frey, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878073/
https://ncbi.nlm.nih.gov/pubmed/27216259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0488-5
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