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Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum

BACKGROUND: The yeast Saccharomyces cerevisiae provides intriguing possibilities for synthetic biology and bioprocess applications, but its use is still constrained by cellular characteristics that limit the product yields. Considering the production of advanced biopharmaceuticals, a major hindrance...

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發表在:Microb Cell Fact
Main Authors: de Ruijter, Jorg C., Koskela, Essi V., Frey, Alexander D.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878073/
https://ncbi.nlm.nih.gov/pubmed/27216259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0488-5
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