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Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum

BACKGROUND: The yeast Saccharomyces cerevisiae provides intriguing possibilities for synthetic biology and bioprocess applications, but its use is still constrained by cellular characteristics that limit the product yields. Considering the production of advanced biopharmaceuticals, a major hindrance...

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Publicado en:Microb Cell Fact
Main Authors: de Ruijter, Jorg C., Koskela, Essi V., Frey, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878073/
https://ncbi.nlm.nih.gov/pubmed/27216259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0488-5
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