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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease

OBJECTIVE: Normal adipose tissue growth and function is critical to maintaining metabolic homeostasis and its excess (e.g. obesity) or absence (e.g. lipodystrophy) is associated with severe metabolic disease. The goal of this study was to understand the mechanisms maintaining healthy adipose tissue...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Lee, Peter L., Tang, Yuefeng, Li, Huawei, Guertin, David A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877665/
https://ncbi.nlm.nih.gov/pubmed/27257602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.001
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