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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease

OBJECTIVE: Normal adipose tissue growth and function is critical to maintaining metabolic homeostasis and its excess (e.g. obesity) or absence (e.g. lipodystrophy) is associated with severe metabolic disease. The goal of this study was to understand the mechanisms maintaining healthy adipose tissue...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Lee, Peter L., Tang, Yuefeng, Li, Huawei, Guertin, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877665/
https://ncbi.nlm.nih.gov/pubmed/27257602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.001
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