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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease

OBJECTIVE: Normal adipose tissue growth and function is critical to maintaining metabolic homeostasis and its excess (e.g. obesity) or absence (e.g. lipodystrophy) is associated with severe metabolic disease. The goal of this study was to understand the mechanisms maintaining healthy adipose tissue...

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Vydáno v:Mol Metab
Hlavní autoři: Lee, Peter L., Tang, Yuefeng, Li, Huawei, Guertin, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877665/
https://ncbi.nlm.nih.gov/pubmed/27257602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.001
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