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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease

OBJECTIVE: Normal adipose tissue growth and function is critical to maintaining metabolic homeostasis and its excess (e.g. obesity) or absence (e.g. lipodystrophy) is associated with severe metabolic disease. The goal of this study was to understand the mechanisms maintaining healthy adipose tissue...

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Bibliografische gegevens
Gepubliceerd in:Mol Metab
Hoofdauteurs: Lee, Peter L., Tang, Yuefeng, Li, Huawei, Guertin, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877665/
https://ncbi.nlm.nih.gov/pubmed/27257602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.001
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