PI3K p110β subunit in leptin receptor expressing cells is required for the acute hypophagia induced by endotoxemia

OBJECTIVE: Hypophagia and increased energy expenditure under inflammatory conditions, such as that observed after bacterial lipopolysaccharide (LPS) administration, are associated with leptin secretion. The hypophagic effect of leptin depends in part on the activation of PI3K signaling pathway. Howe...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Borges, Beatriz C., Garcia-Galiano, David, Rorato, Rodrigo, Elias, Lucila L.K., Elias, Carol F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877663/
https://ncbi.nlm.nih.gov/pubmed/27257598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.03.003
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