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The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K

Mice lacking either CD19 or p110δ have reduced numbers of marginal zone and B1 B cells but normal numbers of naïve B2 cells which occupy the follicles of the lymphoid organs. We show here that mice lacking both CD19 and p110δ have normal B cell development in the bone marrow but have a significant r...

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Detalhes bibliográficos
Main Authors: Kövesdi, Dorottya, Bell, Sarah E, Turner, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065673/
https://ncbi.nlm.nih.gov/pubmed/21487516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.1.2.11796
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