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The development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3K
Mice lacking either CD19 or p110δ have reduced numbers of marginal zone and B1 B cells but normal numbers of naïve B2 cells which occupy the follicles of the lymphoid organs. We show here that mice lacking both CD19 and p110δ have normal B cell development in the bone marrow but have a significant r...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065673/ https://ncbi.nlm.nih.gov/pubmed/21487516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.1.2.11796 |
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