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Molecular Pathways: Breaking the Epithelial Cancer Barrier for Chimeric Antigen Receptor and T-cell Receptor Gene Therapy
Adoptive transfer of T cells genetically engineered to express a tumor-targeting chimeric antigen receptor (CAR) or T cell receptor (CAR) can mediate cancer regression in some patients. CARs are synthetic single chain proteins that employ antibody domains to target cell surface antigens. TCRs are na...
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| Publicado no: | Clin Cancer Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4877620/ https://ncbi.nlm.nih.gov/pubmed/27037253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1294 |
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