An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis

Ulcerative colitis (UC) is a chronic relapsing-remitting form of inflammatory bowel disease (IBD) that increases the risk of colorectal cancer, the third most common malignancy in humans. Oxidative stress is a risk factor for the development of UC. The Keap1-Nrf2-ARE pathway is one of the most impor...

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Vydáno v:Sci Rep
Hlavní autoři: Lu, Meng-Chen, Ji, Jian-Ai, Jiang, Yong-Lin, Chen, Zhi-Yun, Yuan, Zhen-Wei, You, Qi-Dong, Jiang, Zheng-Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877580/
https://ncbi.nlm.nih.gov/pubmed/27215610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26585
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