CPUY192018, a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, alleviates renal inflammation in mice by restricting oxidative stress and NF-κB activation

The Keap1-Nrf2-ARE pathway regulates the constitutive and inducible transcription of various genes that encode detoxification enzymes, antioxidant proteins and anti-inflammatory proteins and has pivotal roles in the defence against cellular oxidative stress. In this study, we investigated the therap...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lu, Meng-Chen, Zhao, Jing, Liu, Yu-Ting, Liu, Tian, Tao, Meng-Min, You, Qi-Dong, Jiang, Zheng-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614503/
https://ncbi.nlm.nih.gov/pubmed/31279986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101266
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados