Novel Mutations in MLH1 and MSH2 Genes in Mexican Patients with Lynch Syndrome

Background. Lynch Syndrome (LS) is characterized by germline mutations in the DNA mismatch repair (MMR) genes MLH1, MSH2, MSH6, and PMS2. This syndrome is inherited in an autosomal dominant pattern and is characterized by early onset colorectal cancer (CRC) and extracolonic tumors. The aim of this s...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Gastroenterol Res Pract
Hlavní autoři: Moreno-Ortiz, Jose Miguel, Ayala-Madrigal, María de la Luz, Corona-Rivera, Jorge Román, Centeno-Flores, Manuel, Maciel-Gutiérrez, Víctor, Franco-Topete, Ramón Antonio, Armendáriz-Borunda, Juan, Hotchkiss, Erin, Pérez-Carbonell, Lucia, Rhees, Jennifer, Boland, Clement Richard, Gutiérrez-Angulo, Melva
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877485/
https://ncbi.nlm.nih.gov/pubmed/27247567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5278024
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