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Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients

AIM: To investigate the protein expression profile of mismatch repair (MMR) genes in suspected cases of Lynch syndrome and to characterize the associated germline mutations. METHODS: Immunohistochemical analysis of tumor samples was performed to determine the protein expression profile of MMR protei...

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Detalhes bibliográficos
Main Authors: Zahary, Mohd Nizam, Kaur, Gurjeet, Abu Hassan, Muhammad Radzi, Singh, Harjinder, Naik, Venkatesh R, Ankathil, Ravindran
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286145/
https://ncbi.nlm.nih.gov/pubmed/22371642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i8.814
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