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Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak

Apoptosis is a regulated form of cell death that proceeds by defined biochemical pathways. Most apoptosis is controlled by interactions between pro-survival and pro-apoptotic Bcl-2 family proteins in which death is often the consequence of permeabilization of the mitochondrial outer membrane. Many d...

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Библиографические подробности
Опубликовано в: :Cell Death Discov
Главные авторы: Megyesi, J, Tarcsafalvi, A, Seng, NSHL, Hodeify, R, Price, PM
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877050/
https://ncbi.nlm.nih.gov/pubmed/27226901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.66
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