Blood protein predictors of brain amyloid for enrichment in clinical trials?

BACKGROUND: Measures of neocortical amyloid burden (NAB) identify individuals who are at substantially greater risk of developing Alzheimer's disease (AD). Blood-based biomarkers predicting NAB would have great utility for the enrichment of AD clinical trials, including large-scale prevention t...

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Dettagli Bibliografici
Pubblicato in:Alzheimers Dement (Amst)
Autori principali: Ashton, Nicholas J., Kiddle, Steven J., Graf, John, Ward, Malcolm, Baird, Alison L., Hye, Abdul, Westwood, Sarah, Wong, Karyuan Vivian, Dobson, Richard J., Rabinovici, Gil D., Miller, Bruce L., Rosen, Howard J., Torres, Andrew, Zhang, Zhanpan, Thurfjell, Lennart, Covin, Antonia, Hehir, Cristina Tan, Baker, David, Bazenet, Chantal, Lovestone, Simon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
Soggetti:
Blood-Based Biomarker
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876903/
https://ncbi.nlm.nih.gov/pubmed/27239491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2014.11.005
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