Blood protein predictors of brain amyloid for enrichment in clinical trials?

BACKGROUND: Measures of neocortical amyloid burden (NAB) identify individuals who are at substantially greater risk of developing Alzheimer's disease (AD). Blood-based biomarkers predicting NAB would have great utility for the enrichment of AD clinical trials, including large-scale prevention t...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Ashton, Nicholas J., Kiddle, Steven J., Graf, John, Ward, Malcolm, Baird, Alison L., Hye, Abdul, Westwood, Sarah, Wong, Karyuan Vivian, Dobson, Richard J., Rabinovici, Gil D., Miller, Bruce L., Rosen, Howard J., Torres, Andrew, Zhang, Zhanpan, Thurfjell, Lennart, Covin, Antonia, Hehir, Cristina Tan, Baker, David, Bazenet, Chantal, Lovestone, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Blood-Based Biomarker
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876903/
https://ncbi.nlm.nih.gov/pubmed/27239491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2014.11.005
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